The hilly city of Sukkur extends from Lansdowne Bridge to Lloyd’s Barrage along the bank of River Indus. Sukkur occupies a vital position as being the historic city of Sindh. Historically centuries ago Muhammad Bin Qasim entered Sindh at Arrore near Sukkur. The Population of upper Sindh has been growing rapidly in the recent times and the need for Medical Education and services in Health sector has been increasing. The idea and the place of Sukkur as the central point for establishment of Medical College and tertiary care Hospital was gaining grounds in the heart and minds of decision makers and people at large. Finally, in the morning of 2nd September, 2003 the foundation stone of Ghulam Muhammad Mahar Medical College (GMMMC) Sukkur was laid down. Every year 100 students belonging to District Sukkur, Ghotki and Khairpur Mir’s are admitted in this College.